Good Health and Well-being

The United Nation’s Sustainable Development Goals (SDGs) are an urgent call for action to tackle 17 major issues affecting people around the world. The third goal ‘good health and well-being’, aims to ‘ensure healthy lives and promote well-being for all at all ages’.

This goal ‘promotes healthy lifestyles, preventative measures and modern, efficient healthcare for everyone.’ Broken down into 13 targets, SDG3 covers a wide range of issues from fighting communicable diseases and reducing maternal mortality, to reducing road injuries and deaths and achieving universal health coverage.

By addressing current issues and practical goals, SDG3 can deliver meaningful and impactful change. For this goal to be met, scientific research needs to be at the heart of the work, creating a partnership between research and action. As reliable research informs and enables decision-makers, each of the 13 targets are turned into tangible, practical results. While progress has been made in promoting good health and well-being, many are still suffering from easily treatable and preventable diseases. For example, the COVID-19 pandemic has had a significant impact on the progress of SDG3, and a sizeable section of the global population still lacks access to healthcare. Scientific research into the causes, prevention and treatment of diseases is essential. It will also aid in recognizing the needs of developing countries, as well as providing a deeper understanding of how to improve healthcare systems and services. In short, it will provide a clear pathway to achieving the overall goal.

In support of this, we have collated a range of articles from our platform to help you develop your knowledge and research in areas that impact the SDG3 goal. Written by authors from across the globe, the articles cover infectious diseases, clinical sciences, health sciences and services, as well as public health. These articles provide valuable insights that support the progress of SDG3.

Infectious Diseases

Monkeypox (mpox) in immunosuppressed patients

S. Ahmed, M. Mohamed, E. Dabou, I. Abuijlan, D. Chandran, N. El-Shall, H. Chopra, K. Dhama

The World Health Organization (WHO) proclaimed a public health emergency in July 2022 due to the emergence of Mpox (formerly monkeypox) while the globe was still dealing with the COVID-19 epidemic.

Willingness-to-pay for a hypothetical Ebola vaccine in Indonesia: A cross-sectional study in Aceh

M. Mudatsir, S. Anwar, J. Fajar, A. Yufika, M. Ferdian, S. Salwiyadi, A. Imanda, R. Azhars, D. Ilham, A. Timur, J. Sahputri, R. Yordani, S. Pramana, Y. Rajamoorthy, A. Wagner, K. Jamil, H. Harapan

Some Ebola vaccines have been developed and tested in phase III clinical trials. However, assessment of whether public have willingness to purchase or not, especially in unaffected areas, is lacking. The aim of this study was to determine willingness to pay (WTP) for a hypothetical Ebola vaccine in Indonesia.

Qualitative analysis of HIV and AIDS disease transmission: impact of awareness, testing and effective follow up

O. Abiodun, O. Adebimpe, J. Ndako, O. Oludoun, B. Aladeitan, M. Adeniyi

Since the early 1980s, human immunodeficiency virus (HIV) and its accompanying acquired immunodeficiency syndrome (AIDS) have spread worldwide, becoming one of the world's major global health issues. From the beginning of the epidemic until 2020, about 79.3 million people became infected, with 36.3 million deaths due to AIDS illnesses.

Clinical Sciences

Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients

H. Gagg, S. Williams, S. Conroy, K. Myers, C. McGarrity-Cottrell, C. Jones, T. Helleday, J. Rantala, O. Rominiyi, S. Danson, S. Collis, G. Wells

With diminishing returns and high clinical failure rates from traditional preclinical and animal-based drug discovery strategies, more emphasis is being placed on alternative drug discovery platforms. Ex vivo approaches represent a departure from both more traditional preclinical animal-based models and clinical-based strategies and aim to address intra-tumoural and inter-patient variability at an earlier stage of drug discovery.

Accelerated atherosclerosis in rheumatoid arthritis: a systematic review

R. Raj, S. Thomas, V. Gorantla

Rheumatoid arthritis (RA) is a highly prevalent, chronic inflammatory condition of the synovial joints that affects approximately 1% of the global population. The pathogenesis of RA is predominantly inflammatory in nature, thereby accelerating the co-occurrence of other immunoinflammatory conditions such as atherosclerosis.

Health Sciences

Characteristics of bibliometric analyses of the complementary, alternative, and integrative medicine literature: A scoping review protocol

J. Ng, H. Liu, A. Shah, L. Wieland, D. Moher

There is a growing body of literature on complementary, alternative, and integrative medicine (CAIM), which offers a holistic approach to health and the maintenance of social and cultural values. Bibliometric analyses are an increasingly commonly used method employing quantitative statistical techniques to understand trends in a particular scientific field.

Dietary knowledge assessment among the patients with type 2 diabetes in Madinah: A cross-sectional study

M. Alharbi, M. Alharbi, A. Surrati, M. Alhilabi, A. Alrashdi, M. Almokhalafi

There is a huge burden of nutrition-related non-communicable diseases, and diabetes is one of the leading chronic nutrition-related diseases affecting more than 500 million people globally. Collecting information regarding the awareness of dietary and nutrition knowledge among diabetic patients is the first step to developing a disease prevention program.

Health Services and Systems

Key concepts for informed health choices: Where’s the evidence?Characteristics of bibliometric analyses of the complementary, alternative, and integrative medicine literature: A scoping review protocol

A. Oxman, I. Chalmers, A. Dahlgren

The Informed Health Choices (IHC) Key Concepts is a framework that provides a basis for developing educational resources and evaluating people’s ability to think critically about health actions. We developed the original Key Concepts framework by reviewing texts and checklists for the public, journalists, and health professionals and collecting structured feedback from an international advisory group.

Crisis-management, Anti-stigma, and Mental Health Literacy Program for University Students (CAMPUS): A preliminary evaluation of suicide prevention

A. Takahasi, H. Tachikawa, A. Takayashiki, T. Maeno, Y. Shiratori, A. Matsuzaki, T. Arai

University students have specific risk factors for suicide, necessitating targeted prevention programs. This preliminary study evaluated the efficacy of the Crisis-management, Anti-stigma, Mental health literacy Program for University Students (CAMPUS) for reduction of risk factors and promotion of preventative behaviors.

Why cost-effectiveness thresholds for global health donors should differ from thresholds for Ministries of Health (and why it matters)

T. Drake, Y. Chi, A. Morton, C. Pitt

Healthcare cost-effectiveness analysis is increasingly used to inform priority-setting in low- and middle-income countries and by global health donors. As part of such analyses, cost-effectiveness thresholds are commonly used to determine what is, or is not, cost-effective. Recent years have seen a shift in best practice from a rule-of-thumb 1x or 3x per capita GDP threshold towards using thresholds that, in theory, reflect the opportunity cost of new investments within a given country.

Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers

B. Antunes, S. Barcaly, I. Kuhn, K. Eagar, C. Bausewein, F. Murtagh, S. Etkind, B. Bowers, S. Dixon, R. Lovick, R. Harding, I. Higginson, F. Shokraneh

Despite the development of patient-centred or patient-reported outcome measures (PCOMs or PROMs) in palliative and end-of-life care over recent years, their routine use in practice faces continuing challenges.

Barriers to compliance with evidence-based guidelines for ventilator-associated pneumonia among critical care nurses: A scoping review

M. Al-Tamimi, F. Refaat, W. Issa

Healthcare organizations provide evidence-based guidelines designed to support nurses in preventing ventilator-associated pneumonia (VAP) in intensive care units (ICUs), but there are barriers to compliance with such guidelines. This review explicitly explored evidence of compliance barriers among critical care nurses.

Public Health

Global research on syndemics: a meta-knowledge analysis (2001-2020)

M. Hossain, N. Saha, T. Rodela, S. Tasnim, T. Nuzhath, T. Roy, J. Burdine, H. Ahmed, E. McKyer, B. Base, P. Ma

Syndemics or synergies of cooccurring epidemics are widely studied across health and social sciences in recent years.

Age-specific incidence of need for long-term care for men and women in Germany 2015: Cross-sectional study comprising 82 million people

L. Haß, S. Tulka, T. Tönnies, A. Hoyer, R. Palm, S. Knippschild, R. Brinks

With the growing number of older people, the number of people in need of long-term care is increasing, too. Official statistics only report on the age-specific prevalence of long-term care. Therefore, there is no data on the age- and sex-specific incidence of the need for care at the population level for Germany available.

F1000Research is an innovative open research publishing venue for researchers in all disciplines, which allows them to publish a wide range of research outputs in Gateways and Collections curated by experts, enables them to accelerate the pace of research discovery, and supports them to get credit for every stage of their research.

Submit now    How it works